Scientists concerned over the number of patients diagnosed each year with mesothelioma and other asbestos related diseases have completed a study of the effects of one particular type of asbestos—crocidolite—on human lung epithelial cells. Unlike previous research, this study employed a systems biology approach to document changes caused by crocidolite in the A549 transcriptome. The research has identified possible asbestos-related genes, generating new scientific hypotheses concerning genes that may be critical to understanding asbestos response in the human lung.
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